Our mission is to prevent heart disease byidentifying genetic causes, personalizingtreatments, and empowering families to takecontrol of their health for future generations.
Schedule a complimentary appointment for a genetic assessment and discuss your concerns with our genetic specialist at Berries Health and Genetics.
To download the Genetic Tests Form, please click HERE
Hyperlipidemia: Refers to elevated levels of lipids (cholesterol and triglycerides) in the blood; caused by lifestyle factors or inherited conditions like FH.
Familial Hypercholesterolemia (FH): Agenetic disorder causing high LDL (“bad cholesterol”) from birth, leading to a higher risk of heart attacks and strokes if untreated.
Lipoprotein(a) [Lp(a)]: A genetically determined lipoprotein carrying cholesterol and fats; elevated levels increase the risk of atherosclerosis, heart attacks, and strokes.
Statins and Genetic Testing: Statins are commonly used to lower cholesterol, but genetic testing can identify individuals at risk of adverse effects, enabling safer and more effective treatment options.
hypercholesterolemia (FH) occurs in about 1 in 250 people, while elevated lipoprotein(a)[Lp(a)] levels can be found in approximately 1 in 5 individuals. Those who carry these genetic conditions can face a risk of heart attacks and strokes that are up to 22 times higher.
Why Consider Berries Health Genetic Testing?
Berries Lipid Panel Testing also detects the following genetic and health abnormalities.
1) Familial (inherited) Hyperlipidemia
2) Hyperlipoproteinemia: including hyperchylomicronemia, lipoprotein metabolism disorder including Lipoprotein A (LPa). APOA, APOB, APOC, APOE
3) Coronary Artery Disease/Atherosclerosis Risk Assessment Score.
4) Hyperlipidemia, Hyperlipoproteinemia, and Atherosclerosis Risk Susceptibility SNPs:
5) Lipid-lowering medication efficacy and adverse event evaluation:
Statins: Atorvastatin (Lipitor), Fluvastatin (Lescol), Lovastatin (Altoprev), Pitavastatin (Livalo), and Rosuvastatin (Crestor).
Ezetimibe (Zetia)
Gemfibrozil (Lopid) and fenofibrate (Tricor)
PCSK9 inhibitors (e.g., alirocumab, evolocumab)
6) Genetic consultation and wellness management.
Limitations of Testing
This test is designed to identify germline pathogenic variants, including single nucleotide polymorphisms (SNPs) and small insertions and deletions (indels) of up to 1 kilobase pair (kbp). It also analyzes mutations within coding regions and the exon-intron boundaries, specifically within 50 base pairs. Any deletions or duplications larger than 1 kbp that are reportable will be confirmed using orthogonal methods before being included in the final report.
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